Nexovas®

Cilnidipine

  • 5 mg Tablet
  • 10 mg Tablet

Cardiovascular

Cilnidipine is a dihydropyridine (DHP) type of calcium channel antagonist which inhibits sympathetic N-type calcium channels in addition to vascular L-type calcium channels. The L-type Ca2+ channel blockade by Cilnidipine affects predominantly vascular smooth muscle, thereby producing vasodilation of peripheral resistance vessels and coronary arteries. The blockade of N-type Ca2+ channels effectively suppresses neurohumoral regulation in the cardiovascular system, including sympathetic nervous system and renin-angiotensin-aldosterone system. Thus, Cilnidipine can reduce various types of complications of hypertension.

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