Cafedon® is recommended for the treatment of various painful and febrile conditions, such as headache (including migraine), backache, toothache, neuralgia, rheumatic pain, and dysmenorrhea. It is also used for the relief of symptoms associated with colds, influenza, and sore throat.

Adults: Take two tablets up to four times daily.Do not exceed eight tablets within 24 hours.
Elderly:Same dosage as for adults.

Cafedon® is contraindicated in individuals with hypersensitivity to paracetamol, caffeine, or any of the other constituents of the medication.

Caution is advised when administering paracetamol to patients with severe renal or hepatic impairment. The risk of overdose is higher in individuals with non-cirrhotic alcoholic liver disease. Patients should avoid excessive consumption of tea or coffee while taking this medication.
Patients must not exceed the recommended dose and should consult a doctor if their headaches or symptoms persist. Additionally, they should not take other paracetamol-containing products concurrently to prevent overdose or adverse effects.

Epidemiological studies on human pregnancy have shown no adverse effects when paracetamol and caffeine are used within the recommended dosage. However, patients should follow their doctor’s advice regarding its use during pregnancy.
Paracetamol and caffeine are excreted in breast milk, but not in clinically significant amounts. Available published data do not contraindicate breastfeeding while taking this medication.

Adverse effects of paracetamol are rare, but hypersensitivity reactions, including skin rash, may occur. There have been very rare reports of blood dyscrasias, such as thrombocytopenia and agranulocytosis, but these were not necessarily linked to paracetamol use.

The absorption of paracetamol may be increased by metoclopramide or domperidone and reduced by cholestyramine.
The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged, regular daily use of paracetamol, leading to an increased risk of bleeding. However, occasional doses have no significant effect.

Immediate treatment is crucial in the management of a paracetamol overdose. Even if symptoms are not immediately apparent, patients must be urgently referred to a hospital for immediate medical attention.
Gastric lavage or activated charcoal administration may be beneficial within one hour of overdose but can still be considered up to four hours afterward. Antidotes such as N-acetylcysteine (NAC) and methionine can protect the liver if administered within 12 hours of overdose.

Store in a cool, dry place below 30ºC. Protect from light.Keep out of reach of children.
