Each gram of ointment contains Mupirocin USP 20 mg.

Mupirocin is a naturally occurring antibiotic. It is an antibacterial agent produced by fermentation using the organism Pseudomonas fluorescens. It is active against a wide range of bacteria responsible for the majority of skin infections, e.g., Staphylococcus aureus. It is also active against certain gram-negative pathogens, such as Escherichia coli and Haemophilus influenzae. Mupirocin inhibits bacterial protein synthesis by reversibly and specifically binding to bacterial isoleucyl transfer-RNA synthetase.

Mupiderm® ointment is indicated for the topical treatment of impetigo due to Staphylococcus aureus and Streptococcus pyogenes.

A small amount of Mupiderm® ointment should be applied to the affected area three times daily.

Mupiderm® ointment is not for ophthalmic or intranasal use. As with other antibacterial products, prolonged use may result in the overgrowth of nonsusceptible organisms, including fungi. When Mupiderm® is used on the face, care should be taken to avoid contact with the eyes.

The effect of the concurrent application of Mupiderm® ointment with other drug products has not been studied.

The drug is classified as Pregnancy Category B. Because animal studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.

It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Mupiderm® is administered to a nursing woman.

The following local adverse reactions have been reported in connection with the use of Mupiderm® ointment:
Burning, stinging, or pain in 1.5% of patients
Itching in 1% of patients
Rash, nausea, erythema, dry skin, tenderness, swelling, contact dermatitis, and increased exudate in less than 1% of patients

Store between 15°C and 30°C. Protect from light. Do not freeze.
Medicine: Keep out of reach of children.
